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Diagnosis of narcolepsy

It is typical that individuals who have some of the symptoms of narcolepsy do not have a conclusive diagnosis of the condition till a number of years after the development of the very first symptoms. Some clients have to wait for over 10 years prior to they get a favorable diagnosis of narcolepsy.

Diagnosis of narcolepsy
Clients who believe they might have narcolepsy must go to a General Practitioner in the very first circumstances. The Epworth scale is a globally accepted methods of measuring of daytime tiredness, the significant sign of narcolepsy.

If a General Practitioner presumes that one of his clients might have narcolepsy he will certainly most likely refer the client to a specialised Sleep Centre. Unless diagnosis is clear from providing symptoms such as cataplexy, clients will most likely remain over night and go through polysomnographic screening. Proof that they pass straight into REM sleep is concerned as being favorable for narcolepsy.

According the the 2nd edition of the International Classification of Sleep Disorders there are 3 kinds of narcolepsy:

  • Narcolepsy with cataplexy
  • Narcolepsy without cataplexy
  • Narcolepsy due to medical conditions

In the very first classification, a favorable diagnosis of narcolepsy is simple as cataplexy is usually a measure of narcolepsy. The client should have had Excessive Daytime Sleepiness daily for a minimum of 3 months and have certain cataplexy. Preferably, polysomnographic tests ought to be performed to validate the diagnosis or additionally levels of orexin in the CSF need to be determined and discovered to be low.

Once more, the client has to have had Excessive Daytime Sleepiness daily for at least 3 months. In this group of clients CSF orexin levels are normally typical however might be low in some clients.

In the 3rd classification, the client needs to have had Excessive Daytime Sleepiness daily for a minimum of 3 months however this have to be accompanied by a considerable medical or neurological condition. Parkinson's illness, Myotonic dystrophy and some kinds of brain injury can trigger this 'secondary narcolepsy'.

In some centres, screening for the tissue type related to narcolepsy might be performed and will certainly supply beneficial confirmatory info.